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Bupropion Online: What You Need to Know Before Buying in Australia

Millie Baylis is a writer and arts worker, living on Wurundjeri land. She writes essays, memoir and commentary, with recent work in Kill Your Darlings, Overland and The Victorian Writer. In 2019 she was a Wheeler Centre Hot Desk fellow and the managing editor of Visible Ink, and in 2020 she is a Moreland Writer in Residence and the Program Coordinator for the Emerging Writers’ Festival.

What drew you to working at EWF?

As an emerging writer myself, I’ve loved attending EWF for years. I think Amazing Babes was the first festival event I ever went to, and I remember being so moved by the incredible work shared by so many amazing women that night. I’ve always loved the welcoming, enthusiastic culture of the festival, as well as the stimulating discussions on the craft of writing and its place in this world.

I’ve worked various jobs in the arts (including at the Wheeler Centre), ushering and getting to listen in on heaps of amazing literary events. Last year, I had a ball working front-of-house for EWF – except for when, while on stage at the National Writers’ Conference trying to get Maria Tumarkin’s mic working, the fly on my pants broke open in front of everyone… but that’s what emerging is all about, right?

It’s extremely exciting to have the chance to contribute to a festival I care about so much now as the Program Coordinator.

Why is celebrating emerging voices in writing important to you?

 There are so many answers to this question! For emerging writers, I think it can be really validating to be invited to share your work and/or ideas in public. That recognition and legitimation can give one the confidence to carry on – something that can be really hard when you’re just starting out. I also believe that writing is a craft that needs practice, and EWF offers a very tangible place for writers to do that – often in front of their first audience too.

There’s so much incredible work being made beyond the more established literary outlets that deserve to be seen and read and listened to. I think it’s so important to help platform this broad range of work, as well as helping writers form connections with each other, from across the continent (and from Aotearoa too.) There’s a shitload of talent to celebrate!

What are you working on outside of EWF?

 I’m working on my own essays – largely to do with mental and physical chronic illness, drawing on memory as well as literature and research to consider the body, trauma, violence, small joys and ideas of ‘healing’.

And I’ve recently joined the team that makes Chronically Chilled, a podcast/radio show about chronic illness and disability, on 3CR.

Is there a book that you feel is the equivalent of a warm hug to you?

To be honest, I’m not often drawn to books of a feelgood nature – but perhaps I should be!

Shadowboxing, the collection of semi-autobiographical linked short stories by Tony Birch, is maybe my favourite book. Birch is so generous and skilled at portraying small, specific moments of his characters’ humanity with such tenderness – I find something profoundly reassuring and hopeful in them.

More recently, Laura McPhee-Browne’s debut novel Cherry Beach made me sob, but it also definitely held me and stroked my hair sweetly after.

If you were an under the sea creature, which would you be?

I want to say a dolphin (from a position of aspiration, rather than recognition). Unlike humans, dolphins have to breathe consciously – it’s not a reflex. There is something staggeringly beautiful about this small but essential detail; that with each breath, they choose to live.

They’re also one of the few animals that are known to have sex for pleasure (and maybe, really, that must influence the breathing thing.) 

Our program launch is all about digital nostalgia – have you got a favourite nostalgic technology throwback?

 Like so many millennials, I spent my pre-teen years – every day at the school library, and every night at home on the family computer via the dial-up modem – talking to other young emos on MSN, and then MySpace. On weekends, I’d take a bus and then a long train to the city to meet internet emos IRL on the Flinders Street Station steps. We’d share headphones to listen to songs on our mp3 players, then return home to change our MSN names to whatever lyrics most matched our mood. (*~* </3 And I’m nothing more than a line in your book </3 *~* – Appears Offline.) I miss the tackiness and earnestness of our curated Myspace profiles back then – one’s choice of Myspace layout and graphics and profile song and ‘who I’d like to meet’ section was an expressive art form! – compared to the sameness of profiles online these days. (Cher Tan, genius emerging writer, wrote a brilliant piece about this btw.)

What are you most excited about for EWF20?

I’m thrilled by how accessible the festival will be online – and how that will mean more people can take part in our huge program of performances, panels, workshops and projects. I’m looking forward to hearing the hard conversations people will have about writing during this intensely unsettling time, to have my thinking challenged, and to experience all kinds of storytelling.

Our program’s out in just a week, and I’m busting to spill its secrets but I won’t, lol. Be sure to check it out when it goes live on June 2 – and I hope to see you during the festival online!

Emerging Writers’ Festival 2020 runs from 16-23 June online.

Bupropion: The Antidepressant That Actually Works – Get It Here. Visit Our Pharmacy ↓


Bupropion in Australia: A Doctor’s Perspective on a Different Kind of Antidepressant

General information only. Bupropion is a prescription-only medicine in Australia. This article does not replace individual medical advice. Always consult a qualified doctor or psychiatrist.

A — Attention: Are You Over 30 and Feeling Flat, Tired, or Stuck?

Many Australians in their 30s, 40s and 50s come to my practice saying the same thing: “I feel flat, I’ve gained weight, my sex drive has disappeared, and I can’t seem to get motivated.” If you have tried a standard antidepressant before, you may know the frustration: the fog lifts a little, but the scales creep up, your energy drops, and intimacy becomes a chore.

Perhaps you are also trying to quit smoking, or you feel that your concentration and drive have faded just when your career and family responsibilities are at their peak. These are real pain points, and they matter more after 30, when metabolism slows and side effects become harder to ignore.

Bupropion is different. It is not an SSRI. It works on a different brain pathway, and for many patients it offers benefits that older antidepressants do not — including weight loss, more energy, and fewer sexual side effects. Let me explain.

I — Interest: What Makes Bupropion Different?

Bupropion is a noradrenaline–dopamine reuptake inhibitor (NDRI). In simple terms, it increases the activity of two brain chemicals — noradrenaline and dopamine — that are closely linked to motivation, alertness, reward and pleasure. This is quite different from SSRIs, which mainly work on serotonin and often cause weight gain, emotional blunting and sexual problems.

In Australia, bupropion is TGA-approved for two major uses:

Bupropion at a glance
Feature What this means for you
Mechanism Boosts noradrenaline and dopamine — the chemicals behind energy, focus and reward.
Weight effect Often causes weight loss or remains weight-neutral; the opposite of many SSRIs.
Sexual side effects Less common than with most standard antidepressants.
Energy and motivation Often improves within the first few weeks; useful for fatigue and sluggishness.
Main cautions Seizure risk, narrow-angle glaucoma, and drug interactions — all assessed by your doctor.
Typical starting dose 150 mg once daily in the morning, usually increased slowly to 300 mg per day.

D — Desire: The Benefits That Matter in Real Life

Weight Loss, Not Weight Gain

One of the most common reasons Australians over 30 ask about bupropion is the effect on weight. Many patients have been on an SSRI and watched their weight climb despite eating the same. Bupropion works differently. It commonly reduces appetite and may slightly increase energy expenditure. In clinical practice, people often lose 1–3 kg or more over several months. If you have struggled with antidepressant-related weight gain, this can feel like a turning point.

More Energy and Motivation

Because bupropion acts on noradrenaline and dopamine, it tends to be activating rather than sedating. Patients describe feeling more alert, more able to start tasks, and less weighed down by brain fog. This is particularly appealing if your depression feels like exhaustion rather than sadness.

Help to Quit Smoking

Bupropion has strong evidence as a smoking-cessation aid. It reduces nicotine cravings and withdrawal symptoms. For many Australians, quitting smoking is one of the most powerful health changes they can make after 30, lowering the risk of heart disease, lung disease and cancer. If you smoke and feel depressed, bupropion may help with both problems at once.

Fewer Sexual Side Effects

Loss of libido, erectile dysfunction and delayed orgasm are frequent reasons people stop antidepressants. Bupropion is much less likely to cause these problems, and it is sometimes added to an SSRI to help reverse sexual side effects. This is a major quality-of-life issue that many patients are afraid to raise — but it matters.

Frequently Asked Questions from Patients Over 30

Here are the practical questions I hear most often, answered from a prescribing doctor’s point of view.

Your concern Doctor’s answer Practical tip
What is the effect of bupropion on intraocular pressure? Bupropion can cause mild pupil dilation. In people with narrow-angle glaucoma, this may trigger an acute angle-closure attack. For most people with healthy eyes or open-angle glaucoma, it does not significantly raise intraocular pressure. It should be used cautiously if you have eye disease. Tell your doctor if you have glaucoma, high eye pressure, or sudden eye pain, blurred vision or halos around lights.
Can bupropion be taken with ibuprofen? Yes, in most cases there is no direct interaction. Ibuprofen can generally be used for short-term pain or inflammation while taking bupropion, provided you have normal kidney function and no history of stomach ulcers or bleeding problems. Tell your doctor if you take ibuprofen regularly, are over 65, or use blood thinners such as warfarin or clopidogrel.
Can bupropion cause weight loss? Yes, weight loss is a recognised effect because bupropion often reduces appetite and may slightly increase metabolism. Many patients lose 1–3 kg or more over several months, especially if they previously gained weight on an SSRI. Monitor your weight. If weight loss becomes unwanted, eat calorie-dense healthy foods and discuss it with your doctor.
How to manage dry mouth from bupropion? Dry mouth is common but manageable. Sip cool water throughout the day, chew sugar-free gum, suck on sugar-free lollies, and use an alcohol-free dry-mouth gel or mouthwash. Limit caffeine and alcohol, and use a humidifier at night if needed. Book regular dental check-ups, because reduced saliva increases the risk of tooth decay.
What is the role of the Australian National Health and Medical Research Council guidelines on bupropion? NHMRC-endorsed smoking-cessation guidelines list bupropion as a first-line pharmacotherapy for nicotine dependence. In depression, NHMRC-endorsed clinical practice guidelines recognise bupropion as an evidence-based antidepressant option. This gives doctors and patients confidence in its use. Ask your GP how these guidelines apply to your individual situation.
What is the interaction between bupropion and SNRIs? Bupropion can increase blood levels of some SNRIs, especially venlafaxine and duloxetine, because it inhibits the CYP2D6 enzyme. Both bupropion and SNRIs can also raise blood pressure and lower the seizure threshold. Combining them requires careful dose adjustment and monitoring by a specialist. Never combine bupropion with an SNRI unless a psychiatrist or GP has planned it specifically.
What is the importance of CYP2D6 metabolism for bupropion? Bupropion itself is mainly metabolised by CYP2B6, but it is a strong inhibitor of CYP2D6. This means it can raise levels of many common medicines, including some beta-blockers, tricyclic antidepressants and antipsychotics. Doctors use this knowledge to prevent side effects and toxic interactions. Bring a complete list of all medicines, supplements and herbal products to every appointment.
How to manage gastrointestinal side effects of bupropion? Nausea, constipation and abdominal discomfort can occur early in treatment. Take bupropion with a light meal, start at 150 mg once daily, avoid heavy or spicy meals, drink enough water, and use ginger or peppermint tea. If constipation occurs, increase fibre, water and gentle exercise. If nausea persists, your doctor may slow the dose increase or add a short-term anti-nausea medicine. Side effects often settle within 1–2 weeks.

A — Action: Talk to Your Doctor About Bupropion Today

If you are over 30 and struggling with low energy, weight gain, sexual side effects from an antidepressant, or nicotine dependence, bupropion may be worth discussing. In my practice, I have seen it change lives — not just by lifting mood, but by giving people their energy, their confidence and their sense of control back.

Here is how to take the next step:

Remember: bupropion is not for everyone. It is not recommended if you have a seizure disorder, an eating disorder such as anorexia or bulimia, or if you are suddenly stopping alcohol, benzodiazepines or certain other medicines. Your doctor will assess your risk and decide whether it is safe for you.

This article is general health information and is not a substitute for individual medical advice. Always consult a registered Australian medical practitioner before starting, changing or stopping any medicine.



2020.emergingwritersfestival.org.au
2020.emergingwritersfestival.org.au
2020.emergingwritersfestival.org.au